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New Data from University of Copenhagen Illuminate Research in Clinical Chemistry
August 25th, 2011
According to the authors of recent research from Hvidovre, Denmark, "Reliable individual risk calculation for trisomy (T) 13, 18, and 21 in first-trimester screening depends on good estimates of the medians for fetal nuchal translucency thickness (NT), free beta-subunit of human chorionic gonadotropin (hCG beta), and pregnancy-associated plasma protein-A (PAPP-A) in maternal plasma from unaffected pregnancies. Means and SDs of these parameters in unaffected and affected pregnancies are used in the risk calculation program."
"Unfortunately, our commercial program for risk calculation (Astraia) did not allow use of local medians. We developed 2 alternative risk calculation...
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Source: VerticalNews Computers (2011-08-25)